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15 Jul 2023
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Congratulations to the CCCG-ALL Study Group on its significant global contributions in paediatric oncology

Congratulations to the China Children's Cancer Group Acute Lymphoblastic Leukemia (CCCG-ALL) Study Group on its significant global contributions in paediatric oncology!

VIVA Foundation for Children with Cancer (VIVA-Singapore) in Singapore’s partnership and collaboration with VIVA China Children’s Cancer Foundation (VIVA-China) has resulted in tremendous success in the CCCG-ALL Study Group. The CCCG-ALL Study Group has now enrolled over 16,000 children across 26 hospitals in China and Hong Kong SAR and published 23 articles on the findings from the study group’s research. In addition, Dr Cai, Director of VIVA China, established a Survivorship Programme at National Children’s Medical Center and Shanghai Children’s Medical Center, which has produced three high-quality publications, including one expert consensus. The collaborative study culminated in a notably high five-year survival rate of 91% for ALL.  

VIVA-Singapore is excited that our partnership with VIVA-China has profound impact in advancing paediatric ALL research and survivorship care in China and beyond — for the children with cancer.

We also thank Dr Pui Ching-Hon, our Chair of External Advisory Board (VIVA-Singapore), for his continuous and invaluable support in this collaboration to advance paediatric ALL research and survivorship care in China, Singapore and the region.

CCCG-ALL Study Group Publications

 

No.TitleJournalYear
1Treatment abandonment in childhood acute lymphoblastic leukemia in China: a retrospective cohort study of the Chinese Children’s Cancer GroupArchives of Disease in Childhood2019
2 “Effect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia chromosome-positive Acute Lymphoblastic Leukemia: A Randomized, Open-label, Multicenter study of the Chinese Children’s Cancer GroupJAMA Oncology2020
3Septicemia after chemotherapy for childhood acute lymphoblastic leukemia in China: A multicenter study CCCG-ALL-2015Cancer Med2020
4Pulse therapy with vincristine and dexamethasone in childhood acute lymphoblastic leukemia: a multicenter, open-label, randomized, phase 3 non-inferiority studyLancet Oncol.2021
5Prognostic factors for CNS control in children with acute lymphoblastic leukemia treated without cranial irradiationBlood2021
6Clinical characteristics of tumor lysis syndrome in childhood acute lymphoblastic leukemiaScientifc Reports2021
7The International Collaboration to Save Children With CancerJAMA Oncology2021
8Reduced Dose Intensity of Daunorubicin During Remission Induction for Low-Risk Patients With Acute Lymphoblastic Leukemia: A Retrospective Cohort Study of the Chinese Children’s Cancer GroupFront Oncol.2022
9Extended vincristine and dexamethasone pulse therapy may not be necessary for children with TCF3‐PBX1 positive acute lymphoblastic leukaemiaBritish Journal of Haematology2022
10A prospective Multicenter Study on Varicella-Zoster Virus Infection in Children with acute lymphoblastic leukemiaFront Cell Infect Microbiol.2022
11Prognostic significance of steroid response in pediatric acute lymphoblastic leukemia: The CCCG-ALL-2015 StudyFront Oncol.2022
12Report of Chinese Children′s Cancer Group acute lymphoblastic leukemia 2015 multicenter studyChin J Pediatr2022
13Prognostic factors of childhood acute lymphoblastic leukemia with TCF3-PBX1 in CCCG-ALL-2015: a multi-center studyCancer2023
14Venous thromboembolism in children with acute lymphoblastic leukemia in China: a report from the Chinese Children’s Cancer Group-ALL-2015Frontiers of Mdicine2023
15Effect of the tyrosine kinase inhibitors on the growth in children with Philadelphia chromosome–positive acute lymphoblastic leukemia: a case–control studyLancet Regional Health – Western Pacific2023
16Causes of death and treatment-related mortality in newly diagnosed childhood acute lymphoblastic leukemia treatment with Chinese Children’s Cancer Group study ALL-2015Annals of Hematology2023
17Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in ChinaLeukemia2023
18Outcome of infants with acute lymphoblastic leukemia treated with the Chinese Children’s Cancer Group Acute Lymphoblastic Leukemia 2015 study protocolHaematologica2024
19COVID-19 infection in children with acute lymphoblastic leukemia in China: Mild clinical course after Omicron infectionChinese Medical Journal2024
20Delineation of features, responses, outcomes, and prognostic factors in pediatric PDGFRB‐positive acute lymphoblastic leukemia patients: A retrospective multicenter studyCancer2024
21Prognostic and therapeutic implication of measurable residual disease levels during remission induction of childhood ALL Blood.2025
22Risk factors and outcomes of asparaginase-associated pancreatitis in pediatric ALL patients Blood.2025
23A Multicenter Study of Acute Abdomen in Children With Acute Lymphoblastic Leukemia: CCCG‐ALL‐2015Cancer Medicine2025
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